1843: The world's first commercial Christmas cards are printed by Sir Henry Cole in London.
May 1843: The first major wagon train headed for the American Northwest sets out with one thousand pioneers from Elm Grove, Missouri on the Oregon Trail.
Dec 1843: Charles Dickens' A Christmas Carol is first published.
2
1844
1844: Charles Goodyear receives a patent for vulcanization, a process to strengthen rubber
1844: George Williams founds the Young Men's Christian Association (YMCA) in London
27 Nov 1844: Joanna Nijhuis passes away in Borne, Overijssel, Nederland.
3
1845
1845: The Great Irish Famine begins, as the potato crop fails.
Mar 1845: The rubber band is invented in England.
1 Apr 1845: Johan Wilhelm Dik is born in Altenberge, Kreis Steinfurt, Nordrhein-Westfalen, Deustschland.
8 May 1845: Johanna Christina Veltrop is born in Slagharen, Hardenberg,Overijssel, Nederland.
Jul 1845: Charles Sturt enters the Simpson Desert in central Australia.
4
1846
1846: The Royal Geographical Society awards Paweł Edmund Strzelecki a Gold Medal "for exploration in the south eastern portion of Australia".[
1846: The Saxophone is patented by Adolphe Sax.
1846: Rotary printing press invented, making rapid printing of newspapers possible.
30 May 1846: Gezina Schopman is born in Hengelo, Overijssel, Nederland.
5
1847
1847: Samuel Colt sells his first revolver pistol to the U.S government.
1847: Charlotte Brontë publishes Jane Eyre under the pen name of Currer Bell.
1847: Emily Brontë publishes Wuthering Heights under the pen name of Ellis Bell.
1847: German inventor and industrialist Werner von Siemens founds Siemens AG & Halske.
6
1848
1848: Karl Marx and Friedrich Engels publish The Communist Manifesto.
1848: Great Britain's first public health law, which creates a national health board and gives cities broad authority to build modern sanitary systems, is passed.
1848: One of the successes of the Revolutions of 1848, the Swiss Federal Constitution, patterned on the US Constitution, enters into force, creating a federal republic and one of the first modern democratic states in Europe.
9 Jul 1848: Gerrit Jan Stegehuis is born in Ambt Almelo, Overijssel, Nederland.